• Exhaled breath condensate pH as a biomarker of COPD severity in ex-smokers 

      Papaioannou, A. I.; Loukides, S.; Minas, M.; Kontogianni, K.; Bakakos, P.; Gourgoulianis, K. I.; Alchanatis, M.; Papiris, S.; Kostikas, K. (2011)
      Endogenous airway acidification, as assessed by exhaled breath condensate (EBC) pH, is present in patients with stable COPD. The aim of this study was to measure EBC pH levels in a large cohort of COPD patients and to ...
    • Exhaled Nitric Oxide in Asthma in Adults: The End is the Beginning? 

      Kostikas, K.; Minas, M.; Papaioannou, A. I.; Papiris, S.; Dweik, R. A. (2011)
      Approximately 20 years after the initial report of the measurement of exhaled nitric oxide (NO) in the exhaled air of humans, numerous publications have evaluated the possible applications of the fraction of exhaled NO ...
    • Inflammatory and oxidative stress biomarkers in allergic rhinitis: the effect of smoking 

      Tanou, K.; Koutsokera, A.; Kiropoulos, T. S.; Maniati, M.; Papaioannou, A. I.; Georga, K.; Zarogiannis, S.; Gourgoulianis, K. I.; Kostikas, K. (2009)
      Accumulating evidence confirms the presence of pan-airway inflammation in allergic rhinitis patients. Smoking is known to affect the asthmatic airway inflammation. However, no study has evaluated the impact of smoking on ...
    • Mitochondrial genetic background plays a role in increasing risk to asthma 

      Zifa, E.; Daniil, Z.; Skoumi, E.; Stavrou, M.; Papadimitriou, K.; Terzenidou, M.; Kostikas, K.; Bagiatis, V.; Gourgoulianis, K. I.; Mamuris, Z. (2012)
      A number of studies suggest that mitochondrial dysfunction plays a role in the pathogenesis of asthma. To shed light for the first time on the role of the mitochondrial genome in the etiology of asthma we analyzed the ...
    • Oxidative stress and inflammatory markers in the exhaled breath condensate of children with OSA 

      Malakasioti, G.; Alexopoulos, E.; Befani, C.; Tanou, K.; Varlami, V.; Ziogas, D.; Liakos, P.; Gourgoulianis, K.; Kaditis, A. G. (2012)
      Obstructive sleep apnea (OSA) in children has been associated with systemic inflammation and oxidative stress. Limited evidence indicates that pediatric OSA is associated with oxidative stress and inflammation in the airway. ...